Role of Endometrium in Fertility Treatment

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Endometrial Thickness:-

One of the most important parameters in infertility treatment is endometrial thickness. The thickness of the endometrial lining is important for embryo implantation.

In the natural cycle as well as in the stimulated cycle, when the egg reaches around 18 mm the endometrium grows under the effect of oestrogen and usually reaches the magic measurement of around 10.3+- 0.3 mm or more and becomes triple layered. If endometrium remains thin in spite of good egg size then that needs an evaluation. 

 

Causes of Thin Endometrium:-

Some important causes of the thin endometrium include chronic pelvic infection, genital tuberculosis, previous history of dilatation and curettage or asherman's syndrome.

It has been seen that when we use clomiphene citrate for ovulation induction, it is associated with a thinner endometrium.

Compared with clomiphene citrate, letrozole has been associated with a thicker endometrium. Gonadotropins represents the most aggressive ovarian stimulation strategy and are associated with highest _estradiol levels which are  believed to result in more pronounced endometrial thickening. In summary, the studies have found live  birth rates are associated with increased endometrial thickness and triple layered pattern of endometrium.

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